Anesthesia and analgesia.
AAALAC International (AAALAC) is a private, non-profit organization that promotes the humane treatment of animals in science through voluntary program assessments and subsequent accreditation.
American Animal Hospital Association.
Condition departing from the normal strain specific expectations; irregularity.
Wire basket used to hold small items that need to be washed such as sipper tubes, cage card holders, reusable enrichment devices, etc. A lid must be placed on the accessory basket before processing through cage wash machines.
For the purpose of the Policy on the Restraint of Research Animals, acclimation is defined as the process used to condition an animal to prolonged physical restraint.
The time period provided to an animal after shipment to allow physiological and psychological stabilization prior to any experimental manipulation.
A colored, plastic card placed over animal cage cards that aid in communication between husbandry, ULAM veterinary, and Investigative personnel. Acetate colors correspond to a specific animal care procedure and could be red, green, clear, yellow or blue. In certain settings, such as aquatic or outdoor housing areas, acetates may not be easily utilized. In those cases, animal identification procedures should be agreed upon by veterinary and investigative personnel as needed and communications will be documented in relevant medical records.
A sticker or white piece of tape placed on the acetate describing information regarding animals within that cage.
Those involving animals currently being treated and/or monitored for a clinical condition, or an experimental condition (e.g. tumor burden, food and water restriction, etc).
Animal Care & Use Office. The ACUO works hand-in-hand with researchers and the IACUC to ensure that all projects adhere to University policies and federal laws that require a review of projects for the humane treatment and judicious use of vertebrate animals.
Animal involved in a study at the University of Michigan, which has a terminal endpoint within seven days of their arrival.
American College of Veterinary Anesthesiologists.
Unlimited supply of food or water.
Adenosine Triphosphate (ATP)
Complex chemical that is present in all organic material and is the universal source of energy used by all living cells (including bacteria). As such, ATP monitoring can be used to quickly assess the sanitization of surfaces or liquid samples. The presence of ATP indicates the presence of organic material, and so a high level of ATP indicates a lack of effective sanitization.
Pharmacological or immunological agent that modifies the effect of other agents (e.g., drugs, vaccines) while having few if any direct effects when given by itself.
Adolescent Rhesus or Baboon
Age between 1-7 years old.
Fish over 90 days old.
Any pig older than 8 weeks of age.
Adult Rhesus or Baboon
Greater than 7 years old.
Last phase of a cycle that circulates the VHP through a catalytic filter to break it down into water vapor and oxygen. Length of this cycle depends on room dimensions.
American Veterinary Medical Association (AVMA)
An association representing veterinarians across the United States focusing on advancing the science and practice of veterinary medicine to improve animal and human health.
Continually released by fish and frogs in their waste, also caused by uneaten food and decaying organic matter; high levels prevent normal respiration and lead to suppressed immune systems. Recommended level = 0 ppm.
Provides pain relief without loss of consciousness.
This encompasses both of the following definitions:
- Local Anesthesia: Temporarily induces loss of sensation to a specific part of the body. May provide pain relief.
- Systemic Anesthesia: Temporarily induces loss of sensation with loss of consciousness. Only provides pain relief due to or during loss of consciousness.
Animal Diagnostic Laboratory (ADL)
Animal Diagnostic Laboratory, part of the Unit for Laboratory Animal Medicine's In-Vivo Animal Core (IVAC).
Animal Enrichment Database (AED)
The central database used to track the approval status and details of all enrichment methods and items used.
Animal Health Contact
The person(s) listed as such on the animal use protocol and the cage card.
Animal Housing Cubicle
A small, self-contained animal housing room constructed within a larger room.
Animal Room Log (e.g. "Room Sheet")
The daily dated log sheet used by husbandry and/or lab staff who do their own care; to record environmental conditions and daily care routines for both animal rooms and non-animal support space (see Non-Animal Support Space Procedures and Documentation SOP).
Includes animal housing rooms or any animal procedure room that can also be used as animal housing space.
Animal Treatment Check-off Sheet
A full-page form which lists an animal's treatments over time, with areas for treatments to be checked off and initialed as they are completed. This is one method for documenting treatments.
Animal Treatment Report (ATR)
A form completed by husbandry personnel requesting veterinary personnel to examine the animal(s). ATRs can be submitted either in paper format or electronically, depending on the species involved.
Animal Use Protocol (AUP)
Animal Use Protocol. A detailed description of the proposed use of laboratory animals. Approved by the Institutional Animal Care & Use Committee (IACUC).
A pharmaceutical used to destroy and eliminate intestinal parasites.
A term used to describe an intestinal parasite which is not 90% cleared following treatment with a specific anthelmintic.
An antibody administered for short-term neutralization of a bacterial toxin.
Animal and Plant Health Inspection Service. APHIS is the agency within the USDA responsible for enforcing the Animal Welfare Act. The USDA receives its authority through federal law (Code of Federal Regulations, Title 7 and 9). Veterinary Medical Officers enforcing the 7 and 9 CFRs inspect research organizations at least annually.
Appropriate Blood Collection Age and Size
Animals must be > 6 weeks of age AND > 15 grams for blood collection. This is due to the fact that animals need to be at least 6 weeks of age to appropriately develop antibodies to exposed pathogens; in addition, at least 25µg of blood is needed for dried blood spot technology. Alternatively, PCR test on environmental swabs, tissues, or feces can be performed.
An adjuvant that uses water or physiologic saline as its background.