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Alternative breeding strategy in which three to four adult females are co-housed with one adult male resulting in multiple pregnancies. All but one female must be removed from the cage prior to the birth of any pups. Justification to house two adult females, one adult male, and two litters in the cage as described by the definition of trio birthing may be submitted to the IACUC. Singly housed pregnant females or stud males should be labeled with a blue tab as described in the Identifying Single Housed Animals SOP.

Hazardous Chemical

A chemical for which there is evidence that acute or chronic health effects may occur in exposed employees. Examples include carcinogens, teratogens, and corrosives.

Hazardous Materials

Hazardous Materials are those materials that constitute a hazard to humans or the environment. The Policy on the Use of Hazardous Materials in Animal Activities applies to the specific hazardous materials listed below when used in conjunction with vertebrate animals:

  • Biological agents requiring handling conditions above Biosafety Level 1 (BSL-1).
  • Biological agents requiring animals to be housed in conditions above Animal Biosafety Level 1 (ABSL-1).
  • Biological specimens (e.g., saliva, blood, and urine) collected from humans or non-human primates.
  • Biological toxins (e.g., Botulinum toxin including cosmetic BOTOX).
  • Activities involving non-exempt recombinant or synthetic nucleic acid molecules technology (rDNA techniques).
  • HHS and USDA Select Agents and Toxins, as defined in Federal Regulations 7 CFR 331, 9 CFR 121, and 42 CFR 73. The current list is available at https://www.selectagents.gov/SelectAgentsandToxinsList.html.
  • Activities involving any radiation producing equipment or materials including ionizing, non-ionizing, x-rays, and lasers.
  • Chemicals designated by the National Institute of Occupational Safety and Health (NIOSH) as hazardous drugs, carcinogens, reproductive hazards, nanoparticles, or toxic chemicals, as well as materials that may have serious impact on the environment during release or disposal that are used in conjunction with animals.

Hazardous Waste Label

Used to label hazardous waste containers. Records hazards contained within the container.

Hazardous Waste Stickers

Stickers used on bins holding chemical waste, including sharps, that have been exposed to Animal Biosafety Level 2 chemicals.


Human-derived substance(s).

Health Report

A set of test results obtained from routine quarterly sentinel testing.

Health/Group Health Record

A record maintained by investigative personnel detailing the care and management (treatments, monitoring, etc.) of a health condition that is performed by the laboratory personnel under the direction of the ULAM veterinary staff.

A single record can be used for multiple animals (a group health record) if:

  • All animals are being treated/monitored in the same way and for the same condition, and
  • The animals are housed together in one cage and share a single clinical number.
  • Components of a health/group health record include:
    • Identification of the animal(s)
    • Clinical observations/monitoring
    • Treatment information
      • Drug
      • Dose
      • Route
      • Time/frequency given
    • Date and initial all entries

Healthy Pup

A young animal that is bright, alert, responsive, hydrated, and otherwise does not appear sick.

Heat Lamps

Infrared bulb used as a heat source that can NOT be Teflon coated due to toxicity.

HEPA Filter

High-Efficiency Particulate Air (HEPA) filters remove 99.97% of all particles 0.3 μm in size.

Home Cage

The cage in which the animal(s) is/are currently housed.

Hymenochirus spp.

Also known as African dwarf frogs.


Artificially induced sleep induced by central nervous system (CNS) depression.