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The process of uniquely marking an animal so it can be differentiated from other animals within a group.

Ignition Source

Some examples of ignition sources include fiber optic light sources, defibrillators, drills, burs, surgical lasers, electrosurgical equipment, and electrocautery equipment.




A method of delivering drugs via direct contact with the skin in a bath.

Immunologic Adjuvant

Agents that non-specifically increase immune responses to specific antigens that are weakly immunogenic.

Import Quarantine (IQ)

Standard ten-week quarantine procedures.

Inactive Case

Those involving animals that are no longer being treated and/or monitored. Cases become inactive when:

  • A clinical condition is resolved by the veterinary staff.
  • The animal is euthanized or un-enrolled from study.
  • The animal is transferred to another laboratory or institution.


Loss or lack of appetite.

Individually Housed

Describes primates housed without tactile contact to another primate. Still has visual and olfactory contact with other primates.


Localized hardening of the soft tissue of the body.

Infectious / Chemical Agent Form

Form that describes the infectious or chemical hazard for each investigator, located in a binder within the containment housing or procedure room.

Infectious Agent (Biologic Agent)

A live organism (e.g. virus, bacteria, rickettsia, fungi, parasite) capable of causing disease in humans/animals, human/animal tissue (normal or diseased) including all human-derived substances.


Inquiry is an official period of time used to collect information associated with a report or allegation. It is also used to determine whether an allegation or incident warrants IACUC investigation.

Institutional Animal Care & Use Committee (IACUC)

Institutional Animal Care & Use Committee. The IACUC is ultimately responsible for approving, requiring modification of, or prohibiting the use of vertebrate animals in research, teaching, and/or testing activities at the University of Michigan. This includes supervision, coordination, training, guidance, and review of every project proposed to include the use of vertebrate animals to ensure that the project has appropriate scientific merit. 


Administration of substances into the brain.

Intradermal (ID)

Administration of substances into the dermis.

Intranasal (IN)

Administration of substances into the nose.


Within the palpebrum.

Intraperitoneal (IP)

Administration of substances into the abdominal cavity.

Intrathecal (IT)

Administration of substances into the subarachnoid space (in the spinal canal but not within the spinal cord).

Intratracheal (IT)

Administration of substances within the trachea.


The initial observation and attempt to pair house two non-human primates.


Investigation is the formal IACUC review of information gathered during the inquiry process. It includes the discussion and evaluation of the relevant facts to determine, for example, whether non-compliance occurred. During this process, the IACUC also quantifies the significance of the incident and identifies the appropriate corrective actions to be taken.


Institutional Official. The IO bears ultimate responsibility for the University of Michigan's Animal Care & Use Program. The IO works closely with the Assistant Vice President for Research – Animal Compliance Oversight and Director of the Animal Care & Use Office; the Assistant Vice President for Research – Animal Resources and U-M Attending Veterinarian; and the Institutional Animal Care & Use Committee Chair to oversee all aspects of animal research at the University of Michigan. 




In-Vivo Animal Core; a division of the Unit for Laboratory Animal Medicine that includes the Animal Diagnostic Laboratory.