# | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z


The process of uniquely marking an animal so it can be differentiated from other animals within a group.

Ignition Source

Some examples of ignition sources include fiber optic light sources, defibrillators, drills, burs, surgical lasers, electrosurgical equipment, and electrocautery equipment.




A method of delivering drugs via direct contact with the skin in a bath.

Immunologic Adjuvant

Agents that non-specifically increase immune responses to specific antigens that are weakly immunogenic.

Import Quarantine (IQ)

Standard ten-week quarantine procedures.

Inactive Case

Those involving animals that are no longer being treated and/or monitored. Cases become inactive when:

  • A clinical condition is resolved by the veterinary staff.
  • The animal is euthanized or un-enrolled from study.
  • The animal is transferred to another laboratory or institution.


Loss or lack of appetite.

Individually Housed

Describes animals housed without tactile contact to another animal. Still has visual and olfactory contact with other animals.


Localized hardening of the soft tissue of the body.

Infectious / Chemical Substance Form

Form that describes the infectious or chemical hazard for each investigator, located in a binder within the containment housing or procedure room.

Infectious Substance (Biologic Substance)

A live organism (e.g. virus, bacteria, rickettsia, fungi, parasite) capable of causing disease in humans/animals, human/animal tissue (normal or diseased) including all human-derived substances.


Administration of a substance over time. Time intervals may be drug- or diluent-specific, or based on veterinary recommendation.


The inquiry is an official period used to collect information associated with a report. The purpose is to gather information pertaining to the report that will be used during the ACC assessment.

Institutional Animal Care & Use Committee (IACUC)

Institutional Animal Care & Use Committee. The IACUC is ultimately responsible for approving, requiring modification of, or prohibiting the use of vertebrate animals in research, teaching, and/or testing activities at the University of Michigan. This includes supervision, coordination, training, guidance, and review of every project proposed to include the use of vertebrate animals to ensure that the project has appropriate scientific merit. 

Institutional Official (IO)

Institutional Official (IO). The IO bears ultimate responsibility for the University of Michigan's Animal Care & Use Program. The IO works closely with the Assistant Vice President for Research – Animal Compliance Oversight and Director of the Animal Care & Use Office; the Assistant Vice President for Research – Animal Resources and U-M Attending Veterinarian; and the Institutional Animal Care & Use Committee Chair to oversee all aspects of animal research at the University of Michigan.


Administration of substances into the brain.

Intradermal (ID)

Administration of substances into the dermis.

Intranasal (IN)

Administration of substances into the nose.


Within the palpebrum.

Intraperitoneal (IP)

Administration of substances into the abdominal cavity.

Intrathecal (IT)

Administration of substances into the subarachnoid space (in the spinal canal but not within the spinal cord).

Intratracheal (IT)

Administration of substances within the trachea.


The initial observation and attempt to pair house two non-human primates.


Lead by the ACC during a convened meeting of at least a quorum of the IACUC; a formal development of a factual record and the examination of that record leading to a decision to determine, for example, whether noncompliance occurred. During the investigation, the IACUC also quantifies the significance of the incident and identifies the appropriate corrective actions to be taken.