Up to 5 weeks of age
Tadpole Hymenochirus spp.
Tadpole Xenopus laevis
3-4 dpf through metamorphosis which is typically around 6-8 weeks of age.
Tadpole Xenopus tropicalis
4 dpf through metamorphosis which is typically around 3-6 weeks of age.
Amputation of the tail of a lamb.
Water coming out of the sink faucet; contains chlorine, which is bad for the fish and will kill them. If used to wash equipment, make sure equipment is dry before using it or rinse it with system water.
Codes used by lab personnel to indicate the type of care provided.
- F: Feed provided (restricted or topped off)
- W: Water bottle topped off
- CW: Changed water bottle
- CC: Cage change performed
- S: New cage started
Technician Time Charges
- Supplies: An amount or quantity of a commodity that is needed outside the normal per-diem fee schedule. For example: additional cages, water bottles when placed long-term on ventilated racks, and non-standard lab requested Personal Protective Equipment (PPE). Note: the time spent and/or service provided must also be charged to the lab monthly.
- Services: To provide time and assistance with a specific job/ task above and beyond standard husbandry duties. For example: euthanasia, amount of time spent changing diabetic animal cages, etc. Technician time may also refer to additional supplies used and provided beyond the normal standard operating procedures.
- Technical Services: Laboratory requested contracted services to be provided by the ULAM Technical Service Team. For example: checking plugs, tagging, tailing, bleeds, injections, measure tumors, etc. Note: the time it takes to provide the service will be billed in 15-minute increments unless management approves otherwise.
- Overtime: Will be charged to time spent providing additional services on weekends, holidays, or after regular working hours (6:00 AM - 4:15 PM). Overtime charges will be a multiplication of the total time on weekends/holidays/after hours by 1.5 (ULAM Business Office personnel will perform this calculation).
Tecniplast Recirculating Tank System
Standard recirculating housing for frogs and fish in which water recirculates throughout the rack.
Temperature Set Point
Room temperature desired to be maintained for each species according to the room temperature table (see Appendix A in the Animal Room Environmental Monitoring SOP).
Sticker that is placed on equipment processed through cage wash machines that indicates highest temperature equipment reached up to 180°F.
An agent capable of causing developmental abnormalities.
This method of eradication is an option for most viral outbreaks in SPF barrier rodent rooms (i.e. rodents housed in microisolator cages). Because microisolator cages are individual biologic units, if appropriate technique is used, there should be minimal risk of viral spread from cage to cage. Eradication is directed at testing one or all mice in each cage and euthanizing any positive cages. This definition may change in unique circumstances.
The Elements Of Fire
The fire tetrahedron can be applied to fires associated with animal use procedures.
Device capable of reading max/current/min temperature as well as relative humidity.
The application of substances directly to the skin for topical effect.
An antigenic poison or venom of plant or animal origin, especially one produced by or derived from microorganisms and causing disease when present at low concentration in the body.
A vaccine administered for long-term protection against a bacterial toxin.
The application of substances directly to the skin for systemic effect.
Complete cage set up; including cage bottom, feeder, and micro-isolation top.
This indicates this animal is being treated for tumor ulceration or a condition secondary to its tumor burden after veterinary consultation or as outlined in the animal use protocol (ex. diet gel will be provided when body condition drops below a 3 out of 5).
Document any laboratory approved ULAM veterinary treatment recommendations (i.e. dietary supplementation, SQ fluids, topical triple antibiotic ointment, etc) on the Tumor Monitoring Form - Cage Card Size (see Appendix A of the Guidelines and SOP on Tumor Monitoring) or on the Tumor Monitoring Form - Notebook Size (see Appendix B of the Guidelines and SOP on Tumor Monitoring) and include the date of treatment, the unique identifier of the cage treated, the treatment itself, and the initials of the person administering the treatment.
Treatment and Observation Sheet
A full-page form used for documenting information for inclusion in the permanent medical record.
A cage card-sized form for recording rodent treatments as they are completed. This is one option for documenting treatments provided by investigative personnel.
Alternative breeding strategy in which two adult females and one adult male are co-housed and left together following the birth of pups, resulting in a maximum of two litters and three adults in a cage. To engage in trio birthing, justification for overcrowding must be submitted to and approved by the IACUC.
Alternative breeding strategy in which two adult females and one adult male are co-housed . Unless otherwise approved, one of the adult females must be removed prior to parturition such that no more than two adults and one litter are in the cage at any given time. Justification for overcrowding may be submitted to the IACUC and if approved, trio birthing may be used. Singly housed pregnant females or stud males should be labeled with a blue tab as described in the Identifying Single Housed Animals SOP.
A printed form provided to truck drivers and husbandry personnel for intra-campus transfers.
Technical Service Team. Part of the Unit for Laboratory Animal Medicine (ULAM). E-mail address: ULAM-Techservice@umich.edu.
A sterile liquid containing the growth products of, or specific substances extracted from the tubercule bacillus.
Applied generally to diseases caused by the tuberculous group of bacteria in the genus Mycobacteria.
Tumor Monitoring Exam
A hands-on exam evaluating for each animal for body condition score, hydration, general behavior, mobility and other contributors to the End-Stage Illness Scoring System in addition to any protocol-specific endpoints like tumor size or tumor ulceration.
Tumor Monitoring Records
A record maintained by investigative personnel that includes the dates and observation codes for animals with experimentally induced tumors. Detailed information on tumor monitoring can be found in the Guidelines and SOP on Tumor Monitoring.