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Treatment (Tx)

This indicates this animal is being treated for tumor ulceration or a condition secondary to its tumor burden after veterinary consultation or as outlined in the animal use protocol (ex. diet gel will be provided when body condition drops below a 3 out of 5).

Document any laboratory approved ULAM veterinary treatment recommendations (i.e. dietary supplementation, SQ fluids, topical triple antibiotic ointment, etc) on the Tumor Monitoring Form - Cage Card Size (see Appendix A of the Guidelines and SOP on Tumor Monitoring) or on the Tumor Monitoring Form - Notebook Size (see Appendix B of the Guidelines and SOP on Tumor Monitoring) and include the date of treatment, the unique identifier of the cage treated, the treatment itself, and the initials of the person administering the treatment.

Treatment and Observation Sheet

A full-page form used for documenting information for inclusion in the permanent medical record.

Treatment Card

A cage card-sized form for recording rodent treatments as they are completed. This is one option for documenting treatments provided by investigative personnel.


Alternative breeding strategy in which two adult females and one adult male are co-housed resulting in two litters. One of the adult females must be removed prior to parturition such that only one litter is born in the cage unless breeding records demonstrating problem breeding are submitted as scientific justification for overcrowding and approved by the IACUC. Singly housed pregnant females or stud males should be labeled with a blue tab as described in the Identifying Single Housed Animals SOP.


Technical Service Team. Part of the Unit for Laboratory Animal Medicine (ULAM). E-mail address: ULAM-Techservice@med.umich.edu.


A sterile liquid containing the growth products of, or specific substances extracted from the tubercule bacillus.

Tuberculosis (TB)

Applied generally to diseases caused by the tuberculous group of bacteria in the genus Mycobacteria.

Tumor Monitoring Exam

A hands-on exam evaluating for each animal for body condition score, hydration, general behavior, mobility and other contributors to the End-Stage Illness Scoring System in addition to any protocol-specific endpoints like tumor size or tumor ulceration.

Tumor Monitoring Records

A record maintained by investigative personnel that includes the dates and observation codes for animals with experimentally induced tumors. Detailed information on tumor monitoring can be found in the Guidelines and SOP on Tumor Monitoring.

U-M Affiliated Instructors/Demonstrators

U-M Affiliated Instructors/Demonstrators are individuals whose primary animal activity is the leading of teaching activities or demonstration of animals or animal procedures.


Unit for Laboratory Animal Medicine. ULAM provides veterinary care to all animals housed on U-M’s campus. ULAM also manages animal ordering and acquisition, animal transport, animal husbandry and housing, personnel training, animal enrichment, and specialized research support services.

ULAM Containment Coordinator

ULAM faculty member with oversight of issues related to animals administered substances known or suspected to be hazardous to humans.

Ultra-PAK (Bio-PAK Prefilter)

An air filtration/dessicator system attached to each rack, except in CC where there are 1-2 installed per pod. The Prefilter is a wire-rimmed filter that is removed, washed and replaced every two weeks. The Ultra-PAK system removes particulate matter from the air and maintains a constant specific level of humidity in the room.

Unhealthy Pup

A young animal that is hunched and scruffy, quiet, lethargic or otherwise appears sick.

Unknown Cause

Veterinary Technical Staff is unable to differentiate whether the condition is spontaneous or induced by research.


United States Department of Agriculture. The USDA's Animal and Plant Health Inspection Service oversees activities involving the use of vertebrate animals at government-registered research institutions. The USDA receives its authority through federal law (Code of Federal Regulations, Title 7 and 9). Veterinary Medical Officers enforcing the 7 and 9 CFRs inspect research organizations at least annually.

USDA-Covered Species

A term that refers to animals whose care is governed by the Animal Welfare Act. USDA-Covered Species include all live or dead warm-blooded animals used in research except birds, rats of the genus Rattus, and mice of the genus Mus bred for research. This also excludes "cold-blooded" animals such as fish, reptiles, and amphibians.

Use Number

The number assigned to each individual order (e.g., F12345) and noted on both the preprinted cage card and the delivery schedule below the PI's name and account number.


United States Pharmacopeia.

Vaporized Hydrogen Peroxide (VHP)

Used to decontaminate animal rooms and/or equipment by using high concentrations of vaporized hydrogen peroxide for an extended period.


Company selling animal(s) or supplies for animal care.

Ventilated Rack Blower Prefilter

An air filtration/dessicator system attached to each rack. The Prefilter is a wire-rimmed filter that is removed, washed and replaced every two weeks.

Veterinary Personnel

All ULAM veterinary technicians, veterinary residents, and faculty veterinarians.

Veterinary Recommendations

These recommendations are made when an animal needs to receive treatments or have medical procedures that are not listed on the animal use protocol and are not being administered directly by the ULAM veterinary staff as treatment for a clinical issue. These recommendations are specifically intended to address an animal's well-being and are not intended for experimental design manipulations unrelated to animal welfare.

Veterinary recommendations are most commonly requested when unexpected or undesired outcomes are occurring on already approved animal use protocols. Veterinary recommendations do not replace amendments to animal use protocols. Veterinary recommendations become a part of an animal's permanent medical record.

Viscous Adjuvant

An adjuvant that includes oil in its makeup.

Visual Examination

Examination performed while the non-human primate is awake in its cage.

Vivarium Dedicated Uniform (VDU)

Long sleeve t-shirts, VDU, or other clothing that is designated as personal protective equipment to be worn and laundered within the animal vivarium space.

Waste Manifest Form

Form provided by EHS to record the start date, building, room number, and description of the environmental hazard(s) placed within the designated EHS approved containers.


Young rabbit that has been weaned from their mother.

Xenopus laevis (X. laevis)

Also known as African Clawed frogs.

Xenopus tropicalis (X. tropicalis)

Also known as Silurana tropicalis or Western Clawed frogs.

Yellow Acetate

Yellow colored transparent plastic card found in a designated supply box in or outside animal rooms.

Yellow or Potentially Contaminated Rooms

Previously contaminated animal room and is now believed to be free from any contaminants. Prior to contamination status release, surveillance results must confirm "clean" status. Certain viral outbreaks may have insufficient information regarding the virus and require animal rooms to placed in "potentially contaminated" state at the discretion of the area veterinarian.

Zebrafish (Danio rerio)

A freshwater fish also known as Danio rerio.

Zoonotic Disease

Diseases that can be transmitted between humans and animals and animals to humans. Sheep may carry Orf and Q-fever, serious diseases that may affect personnel health (see Procedures to Reduce Human Exposure to Orf and Q Fever).