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Local Anesthetic

A local anesthetic is a drug that blocks sensation from a specific area of the body, such as lidocaine or bupivacaine.

Local Processor (LP)

Silver panel outside of rooms have the Edstrom system that displays information pertaining to the environmental conditions (e.g., humidity, light, temperature, etc.) in the room.

Long-Term Personnel

Long-Term Personnel are defined as individuals participating in a research or learning activity for more than 30 consecutive days (1 month) or more than 15 total days over a six-month period.

Loose Animal (Rodent)

Any mouse or rat that falls on the floor of the animal room or procedure room.

Magnahelic Gauge

An instrument that displays the relative pressure of a room.

Major Recovery Surgery

A surgical intervention that penetrates a body cavity (i.e. cranial, thoracic, abdominal, synovial, pelvic, ocular or orbital, skeletal, joint or bone marrow), involves extensive tissue dissection or transection, or has the potential for producing a substantial impairment of a physical or physiological function.

Examples of major survival surgeries include:

  • Tendon/ligament repair or injury
  • Ovariohysterectomy
  • All --otomies (e.g., lararotomy, tracheotomy) and --ectomies
  • -Oscopies that involve incision (e.g., laparascopy)
  • Implantation of central devices
  • Amputation
  • Enucleation
  • Eye surgery involving corneal incision
  • Central cannulation (central approach)
  • Musculoskeletal system repair, injury, or biopsy
  • Extensive tissue dissection/transection (e.g., nerve or muscle cut-down)

Some surgeries may be classified as major or minor depending on various factors, and may be evaluated on a case-by-case basis.

  • Factors that can influence the classification may include the duration of anesthesia, size and location of the incisions, amount of tissue dissection and characteristics of the animal to undergo surgery.

Master Problem List

A list of an animal's health problems that serves as an index to its permanent medical record. It includes each problem, and the dates each was noted and resolved.

McMaster Test

A diagnostic method to provide quantification of intestinal parasite eggs in feces, reported as eggs per gram (EPG).

Medical materials

Consumable supplies used to assist in medical or research procedures. Examples include gauze, syringes, latex gloves, and catheters.

Medical Surveillance Questionnaire

All personnel must be enrolled in the Animal Handler Medical Surveillance Program if they will perform the following tasks:

  1. Handles, restrains, collects specimens from, or administers substances to, live vertebrate animals.
  2. Does not conduct procedures on live animals, but handles animal waste, "unfixed" animal tissues, non-sanitized animal caging/enclosures, or body fluids.
  3. Observes animals or enters animal facility only. No direct contact with animals: inspector, maintenance personnel, etc.

Departments with personnel that meet the requirements of the program will be notified by the eRAM system to complete the Medical Surveillance Questionnaire.

Metamorphosis

A biological process by which some animals, including amphibians, undergo extreme and rapid physical changes sometime after the birth. For aquatic frogs, the tail and gills are reabsorbed and the head shrinks.

MHV

Mouse Hepatitis Virus.

Micro-isolation (MI) Technique

Micro-isolation techniques for rodent cages involve creating controlled environments to house and maintain laboratory rodents, such as mice or rats, in conditions that minimize the risk of external contamination and ensure the animals' health and the validity of experimental results. These techniques include, but not limited to:

  • Working in a laminar flow hood when opening animal cages and handling animals.
  • Housing animals within specially designed isolator caging units.
  • Providing sterilized food, bedding, and environmental enrichment.

Micro-isolator (MI) Top

Micro-isolator (MI) top; used as a cover on rodent cages to prevent contamination within the cage.

Microbiological Sampling

A sample type used for testing to determine whether a colony is contaminated.

Mill Date

Date that the food was formulated by the manufacturer.

Miniature Breed Pig

Pig breeds typically developed or purpose-bred for research that, when fully grown, remain smaller than 200 lbs. Common examples include Yucatan micro- or mini-pigs, Sinclair minipigs, Hanford minipigs, and Gottingen minipigs

Minor

Any person under the age of 18.

Minor Recovery Surgery

A surgical intervention that does not expose a body cavity or that does not ordinarily have the potential to result in impairment of a vital physical or physiological function.

Examples of minor survival surgeries include:

  • Cranial burr holes that do not expose dura or brain
  • Subcutaneous implants
  • Peripheral vessel cannulation (peripheral approach)
  • Castration (scrotal or prescrotal approach)
  • Oral surgery and tooth extractions not involving bone
  • -Oscopies into natural openings that involve biopsy
  • Small digit or tail amputation
  • Surgical repair of superficial injury

MMV

Minute Mouse Virus.

Moribund

A severely debilitated state that precedes imminent death.

MPV

Mouse Parvovirus.

MS

Medical Sciences Building

MSAB

Medical Science Auxiliary Building

MSRB

Medical Science Research Building

MSU

Mobile shelving unit.

Multimodal Analgesia

Multimodal analgesia is defined as a combination of systemic analgesics, like an NSAID and an opioid, or a combination of a systemic analgesic/s and a local anesthetic.

 

 

Naïve

An animal that has not been administered an infectious hazard, human derived substance, or chemical hazard/toxin.

NCRC

North Campus Research Complex

Necropsy Report

A report of gross and/or histologic post mortem findings.

Negative Control

Indicator vial that has no printing on it that is autoclaved in the same liquid filled bottle as the BI (with printing on the vial). A color change indicates thermal degradation has occurred.

Negative Pressure

Room is kept at a lower pressure than the surrounding rooms/hallway, causing air to flow into room from surrounding areas when door is opened.

Neonatal fish

5 to 14-day old fish.

Neonatal Piglet

Any large breed pig weighing less than 15 pounds or miniature breed pig less than 4 weeks of age.

Neonatal Pups

Rat or mouse pups without fur, eyes not open (approximately 10 days old or less).

Neonatal Rabbit Kit

A rabbit kit with no to thin fur, eyes not open (up to approximately 10 – 12 days of age)

Nesting Device

Shepherd Shacks®, igloos.

Nesting Material

Commercially available shredded paper (e.g. Crinkle nest, Envirodri or Enviropaks), nestlets, Alpha Dry or Carefresh bedding.

Net Cleaner

An approved cleaner, e.g., Netsoak or Fritz Pro Aquatic Net Care, used for decontaminating frog and fish nets.

 

Neutral Pressure

No significant flow into or out of room when door is opened.

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