Multimodal analgesia is defined as a combination of systemic analgesics, like an NSAID and an opiate, or a combination of a systemic analgesic/s and a local anesthetic.
An animal that has not been administered an infectious hazard, human derived substance, or chemical hazard/toxin.
A report of gross and/or histologic post mortem findings.
Indicator vial that has no printing on it that is autoclaved in the same liquid filled bottle as the BI (with printing on the vial). A color change indicates thermal degradation has occurred.
Room is kept at a lower pressure than the surrounding rooms/hallway, causing air to flow into room from surrounding areas when door is opened.
Rat or mouse pups without fur, eyes not open (approximately 10 days old or less).
Shepherd Shacks®, igloos.
Commercially available shredded paper (e.g. Crinkle nest, Envirodri or Enviropaks), nestlets, Alpha Dry or Carefresh bedding.
Cleaner used for decontaminating frog and fish nets.
No significant flow into or out of room when door is opened.
New Arrival Cage Card
Pre-printed, electronically generated bar-coded cage card with the following information listed: PI, account #, protocol #, source, species, strain, and arrival date. Lab contact information and special instructions may also be included on the cage card.
New World Monkeys (NWM)
South American monkeys including squirrel monkeys, owl monkeys, marmosets, and tamarins.
Produced by beneficial bacteria in biological filter; converted from toxic ammonia and nitrite; contributes to algal growth. Recommended level = 40 ppm or less.
Produced by beneficial bacteria in biological filter; converted from toxic ammonia; high levels impair respiration and lead to suppressed immune systems. Recommended level = 0 ppm.
Neuromuscular blocking agent.
Non USDA-Covered Species
A term that refers to animals whose care is NOT governed by the Animal Welfare Act. This includes rats of the genus Rattus and mice of the genus Mus bred for research, birds, fish, reptiles, and amphibians.
Non-Animal Support Space
Non-animal support space includes:
- Cage wash
- Food, bedding, supply rooms
- Procedure rooms (only used for procedures, not approved for housing animals)
- Cubicle ante-rooms
- Euthanasia rooms
Non-Human Primate (NHP)
Rhesus macaque, baboon, marmoset.
Chemicals or compounds that do not meet or exceed requirements of USP/NF/BP and may have higher levels of impurities that can introduce unwanted variables or toxic effects. Sterile pharmaceutical grade preparations that are reconstituted, diluted, mixed or have other substances added are also considered non-pharmaceutical grade.
A surgical intervention in which an animal is euthanized before recovery from anesthesia.
Rabbit, ferret, dog, cat, swine, sheep, cow, non-human primate, etc.
Non-Rodent Mammals Conditioned
Animals (e.g., rabbit, ferret, dog, cat, swine, sheep, cow, non-human primate, etc.) with known health history.
Non-Rodent Mammals Non-Conditioned
Animals (e.g., rabbit, ferret, dog, cat, swine, sheep, cow, non-human primate, etc.) with unknown health history.
Nonsteroidal Anti-Inflammatory (NSAID)
Nonsteroidal anti-inflammatory (NSAID) drugs are those such as carprofen, meloxicam, flunixin, or ketoprofen.
Noted Observation (NO)
Conditions that do not initially require the generation of an ATR and require husbandry personnel to place a dated, clear acetate over the cage card describing the condition observed.
Notice of Pesticide Treatment
A report provided by Pest Management Services to the area supervisor which includes observations and treatments performed. These reports are stored in the area supervisor's office.
Athymic, immune compromised mouse that has no T cells.
Room that houses immunodeficient mice.
A multi-purpose detergent used to disinfect cat rooms. Use with a dark purple foamer tip.
These are codes which are to be used by lab personnel to note tumor observations in research subjects.
Observers are individuals who may be in close proximity to animals during a research or learning activity but must not handle the animals or perform any procedures.
Occupational Health Services. The U-M department responsible for providing Michigan Medicine and Ann Arbor campus faculty and staff with services for the prevention, treatment, and rehabilitation of occupational illnesses and injuries.
The Office of Laboratory Animal Welfare. OLAW is a division of the National Institutes of Health (NIH), and the regulating body for all activities funded by the federal government, including the NIH and the National Science Foundation (NSF). OLAW's primary standards are the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy), and the Guide for the Care and Use of Animals (Guide).
Old World Monkeys (OWM)
Asian monkeys including rhesus, cynomolgus, and pigtailed monkeys; or African monkeys including baboons, African green monkeys, and patas monkeys.
Cages that are not transparent but receptive to changes in light, generally used to minimize animal stress levels.
An opiate is an opioid drug such as buprenorphine, fentanyl, or morphine.
Contagious ecthyma, also known as orf or contagious pustular dermatitis, can cause crusting scabs anywhere on the body. Lesions are most frequently seen on the lips, nose, eyelids, tongue, ear, udder, and mucous membranes of sheep. In humans, the disease usually causes a firm, painful nodule on the hands or fingers. This localized lesion usually persists for 1-4 weeks.
Contagious ecthyma is transmissible to humans by direct contact with a lesion or with a contaminated fomite (e.g., bedding, equipment, manure, feed).
Surgical removal of the female reproductive organs.
In the context of the Policy on the Authority and Responsibility of the Quality Assurance Program, oversee refers to conducting reviews of approved animal activities on behalf of the IACUC to ensure that governing standards are satisfied.