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Guidelines
Mar 24, 2023

Guidelines on the Preparation, Storage and Expiration of Injectable Medications

This guideline outlines the expectations for the preparation, storage and expiration of injectable medications.
Guidelines
Mar 10, 2023

Guidelines on the Performance of Surgery in Rodents

This document is intended to provide guidelines for investigators who perform surgical procedure(s) in rodents such as mice, rats, hamsters, gerbils, guinea pigs, etc. All surgical procedures, anesthetics, analgesics, antibiotics or other...
Guidelines
Jan 27, 2023

Physical Exams for Aging Rabbits

Additional procedures associated with older rabbits.
Guidelines
Dec 2, 2022

Guidelines on Experimental Food or Water Restriction or Manipulation in Laboratory Animals

Food and water restriction can be an important and commonly used research tool in many experimental studies. This restriction has the potential to adversely affect an animal's well-being. In keeping within federal and university guidelines, and...
Guidelines
Oct 21, 2022

Guidelines for Acceptable Methods of Identification and Genotyping of Rodents and Zebrafish

To describe procedures to safely and appropriately identify and genotype animals used in laboratory research at the University of Michigan.
Guidelines
Aug 15, 2022

Guidelines for Rodent Euthanasia Procedures for Investigative Personnel

To establish acceptable methods of euthanasia for investigative personnel to perform. The current procedure is composed of two parts: a primary method followed by a secondary method to ensure death and/or prevent revival.
Guidelines
Aug 12, 2022

Guidelines for Documenting Justification for Exceeding Cage Densities

The Guide defines the maximum number of rodents allowed in a given cage space and is the regulatory source for the Guidelines on Mouse and Rat Breeding and Housing Management . This document is intended to provide guidelines for investigators who...
Guidelines
Aug 12, 2022

Guidelines on Mouse and Rat Breeding and Housing Management

To address the health and well-being of mice and rats by ensuring safe breeding practices and population densities. Limiting breeding cage occupancy reduces the incidence of morbidity and mortality due to overcrowding. In all cases, cages should be...
Guidelines
Jan 10, 2022

Guidelines on Anesthesia and Analgesia in Mice

This document has been designed by the ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory mice. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in mice...
Guidelines
Jan 10, 2022

Guidelines on Anesthesia and Analgesia in Rats

This document has been designed by the ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory rats. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in rats...
Guidelines
Sep 8, 2021

Guidelines on Administration of Substances to Laboratory Animals

This document is designed to provide general guidelines about administration of substances to laboratory animals. All procedures must be approved by the Institutional Animal Care & Use Committee (IACUC). The route of administration, intervals...
Guidelines
Apr 23, 2021

Guidelines on Blood Collection

This document is designed to provide general information on blood collection methods for common laboratory animals. All procedures must be approved by the Institutional Animal Care and Use Committee (IACUC). The method of blood collection to be used...
Guidelines
Mar 12, 2021

Guidelines on Medical Records for Investigative Personnel

To define the components of a medical record that are the responsibility of the investigative personnel, and to describe the procedures for generating, maintaining, and storing them.
Guidelines
Jan 15, 2021

Guidelines on Anesthesia and Analgesia in Swine

This set of guidelines was prepared by the ULAM veterinary staff to provide general recommendations for anesthesia and analgesia in laboratory pigs. This is not intended to be an all-inclusive tutorial, and does not factor in specific research-...
Guidelines
Aug 6, 2020

Guidelines on Anesthesia and Analgesia in Cats

This document has been designed by ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory cats. This is not intended to be an all-inclusive tutorial on drug combinations that can be used in cats. The...
Guidelines
Aug 5, 2020

Guidelines on the Performance of Surgery in Non-Rodent Mammals

This document is intended to provide guidelines for investigators who perform surgical procedures in non-rodent mammals including dogs, cats, swine, ferrets, rabbits, ruminants and non-human primates . All surgical procedures, anesthetics,...
Guidelines
Jul 20, 2020

University of Michigan Euthanasia Guidelines

These guidelines are based on the AVMA Guidelines for the Euthanasia of Animals (2020 Edition) . Abbreviation codes are as follows: A = Acceptable - those which consistently produce a humane death when used as the sole means of euthanasia AC =...
Guidelines
Jan 31, 2020

Guidelines on Zebrafish Care and Veterinary Oversight

This document defines the minimum standards of care for zebrafish. It also outlines the veterinary oversight of aquatic species at the University of Michigan. Laboratories may exceed these minimum standards of care, but cannot do less than what is...
Guidelines
Nov 27, 2019

Anesthesia and Sedation Monitoring Guidelines

This document was created by the ULAM veterinary staff as a guideline for anesthesia and sedation monitoring. This is not intended to be an inclusive tutorial on all possible methods and all equipment available for anesthesia monitoring. Detailed...
Guidelines
Nov 21, 2019

Guidelines for the Storage of Sterile Items

To establish procedures for the appropriate handling and storage of sterile items.

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GUIDANCE & OVERSIGHT
Animal Care & Use Office (ACUO)
2800 Plymouth Road
Ann Arbor, MI 48109
Phone: (734) 763-8028
Email: acuoffice@umich.edu

HUSBANDRY & VETERINARY CARE
Unit for Laboratory Animal Medicine (ULAM)
2800 Plymouth Road
Ann Arbor, MI 48109
Phone: (734) 764-0277
Fax: (734) 936-3235
Email: ulam-questions@umich.edu

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