The Guide for the Care and Use of Laboratory Animals (Guide), now in its eighth edition, provides a framework for assisting “institutions in caring for animals in ways judged to be scientifically, technically, and humanely appropriate” and to “...

The United States Department of Agriculture (USDA) Animal Welfare Act and Animal Welfare Regulations (also known as "AWAR" or "AWA/AWR") are a set of standards for the humane care and treatment of mammals (except laboratory-bred rats and mice)...

In 2009, the American College of Veterinary Anesthesiologists (ACVA) revised their set of guidelines for anesthetic monitoring. The goal of the ACVA guidelines is "to improve the level of anesthesia care for veterinary patients. Frequent and...

The purpose of this document is to define minimum standards for personal protective equipment (PPE) when working with research animals at the University of Michigan for the purpose of preventing or controlling personnel exposure to zoonotic...

The Chemical Hygiene Plan (CHP) establishes a written program in accordance with the requirements of the Michigan Occupational Safety and Health Act (MIOSHA) Part 431 Hazardous Work in Laboratories Standard R 325-70100 . The intent of the CHP is to...

This book, an implementation handbook and companion to the Guide for the Care and Use of Laboratory Animals , identifies principles for building an [animal] program and discusses the accountability of institutional leaders, managers, and employees...

The University of Michigan (U-M) Biosafety Manual is a resource for information, guidelines, policies, and procedures that will encourage safe research and eliminate, or reduce, the potential for exposure to biohazards. The information presented...

The University of Michigan is strongly committed to the humane care and use of animals in research, testing, and teaching. Any member of the faculty, staff, or public having reason to question the treatment of animals at U-M should report any...

The publication Approved Drug Products with Therapeutic Equivalence Evaluations (commonly known as the "Orange Book") identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the...